| Abbreviation: 46LA2
|
Load: 15(L)
+ 15(S)
+ 0(CP)
+ 0(EXE)
+ 0(P)
+ 0(ST)
+ 30(LE)
+ 0(ME)
+ 0(SCP)
+ 0(FE)
+ 0(CE)
+ 0(PP)
+ 0(MSCP)
|
| Lecturers in charge: |
dr. sc. Ivna Kocijan |
| Lecturers: |
|
Course description: Lectures will cover the most modern settings molecular biology and experimental
models of molecular biology research.
The central dogma of molecular biology.
Mechanisms of DNA duplication. Replication forks. Okazaki fragments. DNA polymerase.
High reliability replication of the DNA molecule. Mechanisms of DNA repair. Effect
gene. RNA polymerase. Redrawing
the RNA molecule. Reverse transcription. regulation
transcription in prokaryotes and eukaryotes. Genetics of bacteria,
genetic engineering.
Recombinant DNA, restriction endonucleases, ligases. RFLP minisatelli, microsatellites,
SNP.
Genomics. Proteomics. Genetic maps: physical and map-related genes. Molecular
base mutations. Point mutations. Mutagenesis
and cancerogenesis. Gene Therapy,
transgenic animals, 0-mutants and cloning. Biotechnology. At seminars and training
courses
will introduce the basic methods in molecular biology. Electrophoretic techniques and
which allow the separation
and determination of specific nucleic acid fragments
and protein; work with experimental životinjama- isolation early
stages of mammalian embryo,
microinjection of DNA into the oocyte.
|
| Compulsory literature: |
| 1. |
Cooper G.M., Hausman R.E.: Stanica - molekularni pristup, Medicinska naklada, Zagreb, 2004. (odabrana poglavlja) |
| 2. |
Ristov A. i sur.: Metode u molekularnoj biologiji. Institut Ruđer Bošković, Zagreb, 2007. |
| Recommended literature: |
| 3. |
Pavlica M.: Mrežni udžbenik iz genetike. http://www.genetika.biol.pmf.unizg.hr |
|