| Special clinical chemistry |
| Abbreviation: 46LA3
|
Load: 32(L)
+ 28(S)
+ 60(CP)
+ 0(EXE)
+ 0(P)
+ 0(ST)
+ 0(LE)
+ 0(ME)
+ 0(SCP)
+ 0(FE)
+ 0(CE)
+ 0(PP)
+ 0(MSCP)
|
| Lecturers in charge: |
dr. sc. Lovorka Đerek |
| Lecturers: |
|
Course description: The procedure for isolating biological material for special tests. Specific analysis of hemoglobin A, F, and pathological
Hb. Iron-containing proteins: ferrite, transferin, transferin receptors, assay methods and estimates. Acute Phase Proteins:
Positive and Negative. Alpha-1-antitrypsin: deficiency, phenotype determination, clinical relevance. Recommended Algorithm
and Search for Diagnosis and Monitoring of Myocardial Infarction. Biologically important electrolytes and regulation of concentrations
in cells and plasmas. Trace elements: metabolism, regulation, analysis, and significance in clinical practice. Acid-balance
control: parameters to be measured, measurement principles, sample quality. Proteins in the urine. Algorithm Analysis in Diagnosis
of Kidney Disease. Hormones: division, regulation, analytical material, hormone analysis using recommended methods. Vitamins:
Division, Biological Significance, Stability in Biological Material, Standard Methods. Notes on bone metabolism. Notes on
tumor growth: division, methods, analytical assessment. Analyzes in cerebrospinal fluid, from process to material to analysis.
Analytical procedures in the diagnosis of hereditary metabolic diseases. Guidelines for Clinical-Laboratory Diagnosis Development
at the Beginning of the Millennium.
Exercises: Separation of hemoglobin. Immunochemical methods, labeled and unlabeled,
in solution and in gel. Determination of microelements. Quantitative determination of protein containing iron. Mioglobin,
troponin. Immunoglobulins A, G, M. Fibrinogen. Analysis of serum hormones, urine. Probing on metabolic diseases. ABS. PSA
and 15-3, CA 125. Protocols and Rules of Procedure. Maintenance of specific equipment according to good laboratory practice
and quality standards.
|
| Compulsory literature: |
| 1. |
Čepelak I. Štraus B. Dodig S. Labar B. Medicinsko biokemijske smjernice. Zagreb: Medicinska naklada; 2004. |
| 2. |
Topić E. Primorac D. Janković S. Medicinsko biokemijska dijagnostika u kliničkoj praksi. Zagreb: Medicinska naklada; 2004. |
| 3. |
Čvorišćec D. Čepelak I. Štrausova Medicinska biokemija. Zagreb: Medicinska naklada; 2009. |
| 4. |
Dodig S. Imunokemija. Zagreb: Medicinska naklada; 2015 |
| Recommended literature: |
| 5. |
Lothar T. Clinical laboratory diagnostics - use and assessment of clinical laboratory results. First edition. Frankfurt/Main:
The books-Verl. - Ges., 1998.
|
| 6. |
Burtis C. A. Bruns D. E. TietzFundamentals of clinical chemistry and molecular diagnosics. Seventh Edition. St. Louis, Missouri:
Copyright by Saunders, an imprint of Elsevier Inc. 2015.
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