Abbreviation: 46LA2
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Load: 15(L)
+ 10(S)
+ 0(CP)
+ 0(EXE)
+ 0(P)
+ 0(ST)
+ 5(LE)
+ 0(ME)
+ 0(SCP)
+ 0(FE)
+ 0(PL)
+ 0(PCP)
+ 0(MSCP)
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Lecturers in charge: |
dr. sc. Domagoj Marijančević |
Lecturers: |
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Course description: The basic object of the subject is the study of endocrinopathy laboratory diagnostics based on evidence of reduced or increased
concentration of hormones in biological fluids. Students will determine clinically relevant indicators of endocrine disorders
and disease, depending on whether it is a primary disorder in the endocrine gland itself, or suspect secondary dysfunction
due to changes in hormone secretion control mechanisms. An important segment of the course is to introduce analytical techniques
that are applied in laboratory endocrinology. For measuring hormone concentrations, immunochemical and chromatographic methods
are most commonly used today. The choice of method is conditioned by the amount, stability, biochemical and immunological
characteristics of the analyzed hormone. Specific object aims include reviewing physiological and pathophysiological events
that depend on the function of endocrine glands and hormones. Based on the acquired knowledge, the importance of reliable
and rational laboratory diagnostic endocrinopathy will be demonstrated. An active student relationship will be developed according
to the clinical cases that will be encountered in laboratory practice. In seminar tutorials, special focus will be placed
on solving case-oriented problems that include laboratory tests in the process of diagnosing, tracking the pathological condition,
monitoring the effect of therapy and prognosis of the disease.
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Compulsory literature: |
1. |
Čvorišćec D, Čepelak I, ur. Štrausova medicinska biokemija. Medicinska naklada, Zagreb, 2009. |
2. |
Sertić J. i sur. Klinička kemija i molekularna dijagnostika u kliničkoj praksi. Medicinska naklada, Zagreb, 2015. |
3. |
Topić E. i sur. Medicinska biokemija i laboratorijska medicina u kliničkoj praksi. Medicinska naklada, Zagreb, 2017. |
Recommended literature: |
4. |
Burtis C. A. Bruns D. E. TietzFundamentals of clinical chemistry and molecular diagnosics. Seventh Edition. St. Louis, Missouri:
Copyright by Saunders, an imprint of Elsevier Inc. 2015.
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5. |
Lothar Thomas. Clinical Laboratory Diagnostics : Use and Assessment of Clinical Laboratory Results. Amer Assn for Clinical
Chemistry, 1998.
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