| Fundamentals of immunogenetics |
| Abbreviation: 46LA03
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Load: 15(L)
+ 0(S)
+ 0(CP)
+ 0(EXE)
+ 0(P)
+ 0(ST)
+ 15(LE)
+ 0(ME)
+ 0(SCP)
+ 0(FE)
+ 0(PL)
+ 0(PCP)
+ 0(MSCP)
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| Lecturers in charge: |
dr. sc. Renata Žunec |
| Lecturers: |
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Course description: Lectures: Organization Laboratory for Tissue Typing; The main system histocompatibility (HLA); HLA region; The genes HLA class
I and class II; Molecule HLA class I and class II; Biological and clinical significance of HLA; Immunogenetics and solid organ
transplantation; Immunogenetics and transplantation of hematopoietic stem cells; Correlation between HLA genes and disease;
Methods for determining HLA genes, HLA antibodies and HLA
Exercises: Serological HLA; Microlymphocytotoxicity test
(MLCT); Determination of HLA antibodies (serum screening); Cross matching; Molecular typing of HLA; PCR-SSP (polymerase chain
reaction and primers specific for each gene HLA); PCR-SSOP (polymerase chain reaction and probes or spheres of specific single
gene HLA)
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| Compulsory literature: |
| 1. |
Andreis I, Batinić D, Čulo F, Grčević D, Marušić M, Taradi M, Višnjić D. Imunologija. Medicinska naklada, Zagreb, 2004, VI.
izdanje
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| 2. |
Žunec R Molekularna tipizacija HLA-primjena u transplantaciji i dijagnostici. U: Klinička kemija i molekularna dijagnostika
J. Sertić i sur. Medicinska naklada 2008.
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| Recommended literature: |
| 3. |
Guyton AC, Hall JE: Medicinska fiziologija. Medicinska naklada, 11. izdanje, Zagreb, 2006. |
| 4. |
Josip Lukač: Klinička imunologija. Klinička imunologija E-knjiga ISBN: 953-96287-7-6 http://www.sfzg.hr/files/user/isamija/Klinicka_imunologija_skripta.doc |
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